Kenneth E. Thummel
Kenneth Thummel is Professor and Chair of the Department of Pharmaceutics, School of Pharmacy, University of Washington. He received a Bachelor of Science degree in Chemistry from Boise State University in 1981 and a Ph.D. in Pharmaceutical Science from the University of Washington in 1987. He completed a post-doctoral fellowship with Dr. John Schenkman at the University of Connecticut Health Science Center, studying in the field of cytochrome P450 structure and function. In 1989, he joined the faculty at the University of Washington and was promoted to the rank of Professor in 2001. In 1997, he was appointed to the Institute for Public Health Genetics, and currently serves as the program deputy director.
The research interests of Dr. Thummel include the elucidation of genetic, hormonal and environmental factors that regulate cytochrome P450 expression and that contribute to interindividual differences in drug metabolism. He has also worked extensively on the characterization of intestinal CYP3A4-mediated, first-pass drug metabolism, and the use of midazolam as a CYP3A-specific in vivo probe for evaluation and prediction of metabolically based drug-drug interactions.
Dr. Thummel is a Fellow of the American Association for the Advancement of Science and the American Association of Pharmaceutical Sciences. He is also an Associate Editor for Drug Metabolism and Disposition and serves on the editorial board of Pharmacogenetics and Genomics and Pharmaceuticalsx Research.